Rap1 Signaling Prevents L-Type Calcium Channel-Dependent Neurotransmitter Release
نویسندگان
چکیده
منابع مشابه
Rap1 signaling prevents L-type calcium channel-dependent neurotransmitter release.
The small GTPase Rap1 contributes to fear learning and cortico-amygdala plasticity by inhibiting glutamate release from cortical neurons, but mechanisms of this inhibition remain unknown. Conversely, L-type calcium channels (LTCCs) become involved in glutamate release after fear learning and LTP induction. Here, we show that Rap1 deletion in mouse primary cortical neurons increases synaptic ves...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2013
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.5963-11.2013